| Sr.No. | Name | Period |
| PRINCIPAL | ||
| 1 | Charles Morehead | 1845 to 1860 |
| 2 | John Peet | 1860 to 1865 |
| 3 | Herbert John Girand | 1865 to1865 |
| 4 | Robert Haines | 1865 to 1866 |
| 5 | William Guyer Hunter | 1866 to 1876 |
| 6 | Henry Cook | 1876 to 1886 |
| 7 | Henry Vandyke Catrter | 1886 to 1888 |
| 8 | Well Ngton Gray | 1888 to 1893 |
| 9 | George A. Maconachie | 1893 to 1897 |
| 10 | William Keith Hatch | 1897 to 1903 |
| 11 | Henry P. Dimmock | 1903 to 1911 |
| 12 | LT. COL. C.H.I. Meyer | 1911 to 1913 |
| 13 | LT.COL. L. F. Childe | 1913 to 1915 |
| 14 | L. T. COL. A. Street | 1915 to 1919 |
| DEAN | ||
| 15 | L. T. COL. R. Markham Carter | 1919 to 1921 |
| 16 | Major B. Higham | 1921 to 1925 |
| 17 | Major S. L. Bhatia | 1925 to 1937 |
| PRINCIPAL | ||
| 18 | L. T. COL. S. L. Bhatia | 1937 to 1941 |
| 19 | Rao Bhadur R. C. Motwani | 1941 to 1944 |
| 20 | Lieut. Colone Jelal M. Shah | 1944 to 1947 |
| DEAN (POST INDEPENDENT PERIOD) | ||
| 21 | Dr. Settha D. P. | 1947 to 1956 |
| 22 | Dr. Telang D. M. | 1956 to 1960 |
| 23 | Dr. D. Quardra | 1960 to 1962 |
| 24 | Dr. Virkar D. V | 1962 to 1968 |
| 25 | Dr. Karandikar. G. K. | 1968 to 1972 |
| 26 | Dr. Lele. R. D | 1972 to 1973 |
| 27 | Dr. Gadgil | 1973 to 1974 |
| 28 | Dr. Sharma. K. D. | 1974 to 1979 |
| 29 | Dr. Anjaneyullu. R. | 1979 to 1980 |
| 30 | Dr. Deodhare. S. G. | 1980 to 1984 |
| 31 | Dr. Dube P. N. | 1984 to 1984 |
| 32 | Dr. Chandrikapure R. S. | 1984 to 1986 |
| 33 | Dr. Sankholkar P. | 1986 to 1986 |
| 34 | Dr. Vare A M. | 1986 to 1988 |
| 35 | Dr.Sathe P. V. | 1988 to 1988 |
| 36 | Dr. Ganeriwal S. K. | 1988 to 1992 |
| 37 | Dr. (Mrs) Warerkar | 1992 to 1993 |
| 38 | Dr.Shirolkar S. P. | 1993 to 1995 |
| 39 | Dr. Dongaonkkar D. G. | 1995 to 1998 |
| 40 | Dr. Mohanti A. C. | 1998 to 2000 |
| 41 | Dr. Bhutada. V. R. | No 2000 to July 2001 |
| 42 | Dr. Deshpande S. G. | July 2001 to Feb. 2003 |
| 43 | Dr. Daver. G. B. | Feb. 2003 to July 2004 |
| 44 | Dr. Shingare P. I. | July 2004 to May 2008 |
| 45 | Dr. Sabnis B. M. | May 2008 to Dec. 2008 |
| 46 | Dr. Inamdar R. S. | Jan 2009 to Feb 2010 |
| 47 | Dr, Lahane. T.P. | Feb 2010 to Oct. 2017 |
| 48 | Dr. Nanandkar S. D. | Oct 2017 to June 2018 |
| 49 | Dr. Tayade M. B. | June 2018 to Dec. 2018 |
| 50 | Dr. Chandanwale A. S. | Dec. 2018 to Till Date |
